Metabolomics

TitleMetabolomics
Publication TypeBook Chapter
Year of Publication2004
AuthorsJonathan Arnold, J. H.-B. Schuttler, D. Battogtokh, J. Griffith, Ismailcem Budak Arpinar, S. Bhandarkar, Krzysztof Kochut, E. Kraemer, J. A. Miller, Amit Sheth, G. Strobel, T. Taha, Boanerges Aleman-Meza, D. Logan, Jereme Doss, Latreace Harris, Abassi Nyong, S. Datta
Book TitleHandbook of Industrial Mycology
Pagination597-633
Date Published03/2004
PublisherNew York: Marcel Dekker
CityNew York
Keywordsfungal, genomics
Abstract

Metabolomics is the computing of emergent properties of biological systems such as development, biological clocks, and infection processes from kinetic models of DNA, RNA, and proteins. These kinetic models are used to guide the process of gene-validated product discovery to transform medicine, industry, and agriculture. The ultimate challenge of genetics is to predict global properties of the organism, properties not necessarily manifested by individual subcomponents within the cell. Some of these properties only make sense with respect to the organism as a whole (e.g., pathogenicity lifestyle) or life itself. These complex traits controlled by many genes represent the ultimate challenge in seeking an explanation in terms of detailed molecular mechanisms in the cell.

Full Text

Jonathan Arnold, J. H.-B. Schuttler, D. Logan, D. Battogtokh, J. Griffith, B. Arpinar, S. Bhandarkar, S. Datta, K. J. Kochut, E. Kraemer, J. A. Miller, A. Sheth, G. Strobel, T. Taha, B. Aleman-Meza, J. Doss, L. Harris, A. Nyong. S. Datta. "“Metabolomics." Handbook of Industrial Mycology, Zhiqiang An (Ed.), New York: Marcel Dekker, 2004, ch. 22, pp. 597-–633, ch. 22, pp. 597-633. New York: Marcel Dekker. Zhiqiang An (Ed.)